Gene information
Official symbol MASP1
Official full name mannan binding lectin serine peptidase 1
Gene type protein-coding gene
Chromosome3q27.3
Alias symbolMASP
Previous symbolCRARF; PRSS5
Gene familySerine proteases; Sushi domain containing; Complement system activation components
Resources
Entrez Gene 5648
HGNC HGNC:6901
Ensembl ENSG00000127241
Vega OTTHUMG00000156461
UCSC uc003frh.3
GO terms: 12 records
GO Description Category LogP Number of genes Detail
GO:0002252 immune effector process GO Biological Processes -24.2648770 43 More
GO:0002253 activation of immune response GO Biological Processes -3.86084748 14 More
GO:0004175 endopeptidase activity GO Molecular Functions -25.2809598 44 More
GO:0004252 serine-type endopeptidase activity GO Molecular Functions -24.0834770 30 More
GO:0005509 calcium ion binding GO Molecular Functions -14.7764642 80 More
GO:0006959 humoral immune response GO Biological Processes -20.5068158 33 More
GO:0008233 peptidase activity GO Molecular Functions -21.0463733 46 More
GO:0008236 serine-type peptidase activity GO Molecular Functions -23.9716175 31 More
GO:0017171 serine hydrolase activity GO Molecular Functions -24.8900503 32 More
GO:0042803 protein homodimerization activity GO Molecular Functions -14.2815375 77 More
GO:0048306 calcium-dependent protein binding GO Molecular Functions -6.71779738 10 More
GO:0050778 positive regulation of immune response GO Biological Processes -17.2528761 40 More
KEGG pathways: 3 records
KEGG Description Category LogP Number of genes Detail
hsa04610 Complement and coagulation cascades KEGG Pathway -50.1154932 39 More
hsa05150 Staphylococcus aureus infection KEGG Pathway -9.38905356 13 More
hsa05171 Coronavirus disease - COVID-19 KEGG Pathway -24.8179886 34 More
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
mannan-binding lectin serine protease 1 proteomics myocardial infarction[diagnosis] myocardial infarction Holt CB et al. Eur Heart J Acute Cardiovasc Care. 2014
mannan-binding lectin serine protease 1 proteomics myocardial infarction[diagnosis] myocardial infarction Vengen IT et al. Sci Rep. 2017
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